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This isn't an answer so much as some information related to your question.

We have an open GitHub [issue](https://github.com/codidact/qpixel/issues/680) to add searching on reactions.  We can already search by post type, category, user, score, and other things, so this seems a reasonable extension.  We haven't gotten to it yet, though.

That wouldn't fully address your request -- you could do it, but you'd have to repeat the search any time you wanted to find such questions.  However, we're also working on [filters](https://meta.codidact.com/posts/285370) -- there's a draft pull request, not just aspiration -- which will let you change the default view of a category.

If we had search by reaction, and if we further had search questions by *answer* reaction, then it would seem feasible to also add the capability to filters.  I hadn't previously considered "search questions by properties of answers", so I don't know how hard that is.

So... we don't have this yet, and several pieces would have to come together, but I can see a path toward what you're asking for.  I've linked this question from that search issue, and I'll ask about "search questions by answer properties" -- which has applications beyond reactions, too.  ("Questions with no answer scores above X", for example.)  It won't be soon, but it's on our radar now.